McDaniel-Milliken holds an M.S. in library and information sciences from the University of South Carolina and M.M. and B.M. degrees in vocal performance from Winthrop. She is the music library director and an instructor of opera literature at Winthrop.
She has performed the title roles in opera productions of Suor Angelica and Dido and Aeneas. McDaniel-Milliken was co-director of Winthrop's production of Dido and Aeneas and the director of the Winthrop Department of Music production of Red, White, and New: American One-Act Operas. She also served as assistant director of Gilbert and Sullivan's The Gondoliers. She has been the soprano soloist in performances of Handel's Messiah, Vivaldi's Gloria, Saint-Saens' Christmas Oratorio, Britten's A Ceremony of Carols, Schubert's Mass in G, Faure's Requiem, and many other sacred works. She has performed in numerous recitals, choral concerts, festivals, and musicals throughout York, Richland, and Mecklenburg counties and still performs in Winthrop's vocal faculty recitals.
McDaniel-Milliken also is director of music at Quail Hollow Presbyterian Church in Charlotte, N.C.